A Novel Oxidovanadium (IV)-Orotate Complex as an Alternative Antidiabetic Agent: Synthesis, Characterization, and Biological Assessments

Figure 5

Histology of the pancreas. Pancreatic tissue was collected from each animal after 30 days of treatment. The tissue was sectioned, stained using H & E, and imaged using standard light microscopy at 400 x magnifications. Double-sided arrows () denote an islet of Langerhans. (a) Pancreas from healthy control animal (Group I), (b,c) Pancreas from STZ-treated diabetic animal (Group II), (d,e) Pancreas from animal treated with oxidovanadium(IV) sulfate alone (Group III), (f) Pancreas from animal treated with oxidovanadium (IV)-orotate complex (Group III).