Impact of Intravenous Fluid Challenge Infusion Time on Macrocirculation and Endothelial Glycocalyx in Surgical and Critically Ill Patients
Table 2
Perfused boundary region values.
Variable
group
timepoint
Group Fast
Group Slow
p value
Non-RESPONDER
RESPONDER
p value
(n=32)
(n=34)
(n=27)
(n=39)
Perfused boundary region
all
T0
1.80
1.72 to 2.05
1.89
1.76 to 2.08
0.176
1.89
1.78 to 2.04
1.86
1.76 to 2.10
0.667
T1
1.91
1.75 to 2.13
1.96
1.85 to 2.26
0.256
1.89
1.78 to 2.10
2.10
1.86 to 2.28
0.043
T60
1.89
1.77 to 2.08
2.02
1.72 to 2.16
0.576
1.88
1.74 to 2.13
2.04
1.79 to 2.24
0.146
p value
0.095
0.224
0.521
0.014
OR
T0
1.77
1.70 to 1.94
1.86
1.76 to 2.04
0.118
1.85
1.73 to 1.95
1.76
1.73 to 2.02
0.336
T1
1.90
1.77 to 2.08
1.96
1.79 to 2.27
0.171
1.88
1.78 to 2.12
1.96
1.79 to 2.26
0.286
T20
1.88
1.71 to 2.09
2.04
1.72 to 2.21
0.165
1.98
1.72 to 2.15
1.99
1.73 to 2.14
0.985
T40
1.99
1.74 to 2.17
1.89
1.62 to 2.05
0.263
1.94
1.74 to 2.15
1.87
1.64 to 2.04
0.346
T60
1.81
1.74 to 2.00
1.88
1.71 to 2.16
0.584
1.83
1.70 to 1.99
1.90
1.72 to 2.12
0.404
p value
0.093
0.034
0.078
0.154
SEP
T0
2.12
1.96 to 2.30
2.02
1.89 to 2.22
0.560
1.97
1.75 to 2.16
1.96
1.85 to 2.18
0.857
T1
2.10
1.78 to 2.31
1.96
1.90 to 2.08
0.427
1.99
1.78 to 2.07
2.28
2.04 to 2.52
0.027
T60
2.01
1.91 to 2.25
2.15
1.84 to 2.17
0.791
2.07
1.85 to 2.17
2.19
2.05 to 2.33
0.115
T120
1.87
1.77 to 2.22
2.01
1.91 to 2.29
0.418
1.91
1.79 to 2.01
2.05
2.03 to 2.47
0.056
p value
0.212
0.867
0.376
0.290
Values are displayed as median (interquartile range). Significant difference towards baseline (Friedman test), intergroup significant difference marked in bold letters. Abbreviations: Group Fast: fast administration; Group Slow: slow administration; OR: operative cohort; SEP: patients with sepsis/septic shock.
