Assessment of Biochemical and Densitometric Markers of Calcium-Phosphate Metabolism in the Groups of Patients with Multiple Sclerosis Selected due to the Serum Level of Vitamin D₃

Table 3

Comparison of biochemical markers of calcium-phosphate metabolism in the subgroups of patients with deficiency, insufficiency, and normal level of 25-hydroxycholecalciferol.

Parameter	VitDd; n=30	VitDi; n=45	VitDn; n=7	p
ALP [U/L]	71.8 ± 35.3	61.7 ± 18.0	64.6 ± 14.8	0.22
abnormal ALP [%]	7.1	5.3	0	0.75
P [mmol/l]	0.95 ± 0.15	0.96 ± 0.13	0.98 ± 0.14	0.90
Hypophosphatemia [%]	21.4	0	0	0.039
Ca^2+ [mmol/l]	0.92 ± 0.09	0.94 ± 0.04	0.91 ± 0.04	0.42
hypocalcemia [%]	100.0	100.0	100.0	1.0
PTH [pg/ml]	40.7 ± 14.1	34.4 ±15.4	27.3 ± 7.7	0.019
hyperPTH [%]	16.1	10.5	0	0.46

VitD₃: 25-hydroxycholecalciferol, VitDd: vitamin D₃ deficiency, VitDi: vitamin D₃ insufficiency, VitDn: normal vitamin D_3, ALP: alkaline phosphatase, P: phosphorus, Ca²⁺: ionized calcium, PTH: parathyroid hormone, HyperPTH: hyperparathormonemia