Research Article
Integration of Gene Expression Profile Data to Screen and Verify Hub Genes Involved in Osteoarthritis
Table 3
Signaling pathway enrichment analysis of DEGs function in osteoarthritis.
| | Expression | Term | Description | Gene Count | P-Value |
| | DOWN- DEGs | hsa04060 | Cytokine-cytokine receptor interaction | 5 | 0.036430433 | | hsa00603 | Glycosphingolipid biosynthesis - globoseries | 2 | 0.074364973 |
| | UP-DEGs | hsa04668 | TNF signaling pathway | 13 | 3.53E-09 | | hsa04380 | Osteoclast differentiation | 9 | 1.61E-04 | | hsa04010 | MAPK signaling pathway | 12 | 2.13E-04 | | hsa05134 | Legionellosis | 6 | 4.41E-04 | | hsa05132 | Salmonella infection | 7 | 4.52E-04 | | hsa05219 | Bladder cancer | 5 | 0.001397716 | | hsa05144 | Malaria | 5 | 0.002719238 | | hsa05166 | HTLV-I infection | 10 | 0.003418411 | | hsa04064 | NF-kappa B signaling pathway | 6 | 0.003787905 | | hsa05323 | Rheumatoid arthritis | 6 | 0.003978832 |
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