Research Article
Cross-Protective Efficacy of Monovalent Live Influenza B Vaccines against Genetically Different Lineages of B/Victoria and B/Yamagata in Ferrets
Table 5
Antibody response to influenza B viruses.
| | Vaccine administered (groups) | Antigen | | B/Vic WT (GMT) | B/Yam WT (GMT) | | Day 0 | Day 21 | Fold increase | Day 0 | Day 21 | Fold increase |
| | HAI test |
| | B/Vic LAIV (groups 1-2) | 5.0 | 36.0 | 7.2 | 5.0 | 5.0 | 1.0 |
| | B/Yam LAIV (groups 3-4) | 5.0 | 5.0 | 1.0 | 5.0 | 90.0 | 18.0 |
| | Groups 5-7 (controls) | 5.0 | 5.0 | 1.0 | 5.0 | 5.0 | 1.0 |
| | MN test |
| | B/Vic LAIV (groups 1-2) | 5.0 | 359.2 | 71.8 | 5.0 | 5.0 | 1.0 |
| | B/Yam LAIV (groups 3-4) | 5.0 | 5.0 | 1.0 | 5.0 | 226.3 | 45.3 |
| | Groups 5-7 (controls) | 5.0 | 5.0 | 1.0 | 5.0 | 5.0 | 1.0 |
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