High Ghrelin Level Predicts the Curve Progression of Adolescent Idiopathic Scoliosis Girls

Figure 2

Receiver operator characteristic (ROC) curves for the accuracy of ghrelin and leptin to predict the curve progression in AIS girls were analyzed. Ghrelin levels of >6.48 ng/ml were predictive for curve progression with 70.00 % sensitivity and 72.31 % specificity, and the area under the curve (AUC) was 0.741 (95 % confidence interval 0.646-0.821). Leptin levels of ≤5.67 ng/ml were predictive for curve progression with 57.50 % sensitivity and 66.15 % specificity, and the AUC was 0.580 (95 % confidence interval 0.480–0.676).