Integrative Network Analysis Reveals a MicroRNA-Based Signature for Prognosis Prediction of Epithelial Ovarian Cancer

Figure 1

Network inference analysis reveals four major regulatory networks of the mesenchymal subtype. (a) The mRNA-miRNA network shows the relationships between four key miRNAs and the EMT signature genes. (b) The four-miRNA signature was significantly lower in the mesenchymal subtype in the TCGA dataset than the other three subtypes. (c) Significant correlation between FN1 expression and the four-miRNA expression in the TCGA dataset.

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