RNA Sequencing Analysis of Molecular Basis of Sodium Butyrate-Induced Growth Inhibition on Colorectal Cancer Cell Lines

Figure 5

MCM2-7 knockdown inhibited proliferation of HCT116 cells. (a) MCM2, MCM3, MCM5, and MCM7 siRNA were transfected into HCT116 cell and their expressions were detected by Western blot. HCT116 cells with knockdown of MCM2, MCM3, MCM5, and MCM7 were examined by CCK8 assay (b) and by apoptotic assay (c). Data are presented as mean ± SD; P < 0.05; P < 0.001.

(a)

(b)

(c)