Knockdown of PHF5A Inhibits Migration and Invasion of HCC Cells via Downregulating NF-κB Signaling

Figure 3

Knockdown of PHF5A inhibits migration and invasion of HCC cells. (a) qPCR assay of PHF5A in indicated stable cell lines. (b) Western blotting of PHF5A in indicated stable cell lines, and α-tubulin is served as the loading control. (c) Representative micrographs (left panel) and quantification (right panel) of wound healing assay both illustrated that inhibition of PHF5A downregulates migration of HCC cells. (d) Representative micrographs (left panel) and quantification (right panel) of Transwell matrix penetration assay suggest that knockdown of PHF5A can inhibit invasion of HCC cells. P < 0.05.

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