A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line

<div>Chemical structure of (a) ethyl-2-[6-(4-chlorophenyl)-1-methyl-4H-benzo[e][1,2,4]triazolo[3,4-c][1,2,4]triazepin-4 yl] acetate (ITH-47) and (b) 2-ethyl-3-<i>O</i>-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) (ACD/ChemSketch Freeware version 12.0).</div>

BioMed Research International

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Figure 1

Figure 1: A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line 