A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line

Figure 6

PI (FL3 log) against annexin V (FL1 log) histogram of vehicle-treated (a), ESE15-ol-treated (b), ITH-47-treated (c), and combination-treated (d) MCF-7 cells subsequent to 48 hours of treatment. Results revealed a significant rise in the number of cells present in early phases of apoptosis in combination-treated cells in comparison with the vehicle control-treated cells.

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