A Combination of an Antimitotic and a Bromodomain 4 Inhibitor Synergistically Inhibits the Metastatic MDA-MB-231 Breast Cancer Cell Line

Figure 9

Western blot analysis of BRD-4 and c-Myc protein expression levels. Exposure of MCF-7 to ITH-47, ESE-15-ol, and combination treatment resulted in a minor increase in both BRD4 and c-Myc protein levels when compared to the vehicle-treated cells ( value >0.05).