Extract from Bougainvillea xbuttiana (Variety Orange) Inhibits Production of LPS-Induced Inflammatory Mediators in Macrophages and Exerts a Protective Effect In Vivo

Figure 2

Effect of BxbO extract on mice protection from LPS-induced septic shock. (a) Groups of mice were randomly distributed in four different groups which consisted by 5 mice/group and i.p. injected with LPS (with 7.8, 15.6, 31.2, and 62.4 mg/kg) and the survival rates were recorded every 24 hours over a period of 144 hours. (b) Groups of mice were randomly distributed in four different groups and orally treated with 2 mg/kg of BxbO extract at 1 h after or 1 before or together LPS (62.4 mg/kg) and the survival rates were recorded every 24 hours over a period of 144 hours.

(a)

(b)