Extract from Bougainvillea xbuttiana (Variety Orange) Inhibits Production of LPS-Induced Inflammatory Mediators in Macrophages and Exerts a Protective Effect In Vivo

Figure 3

Effect of BxbO extract on mediator production from LPS-induced septic shock. Groups of mice were randomly distributed in four different groups which consisted of 5 mice/group and i.p. injected with LPS (31.2 mg/kg) or orally treated with 2 mg/kg of BxbO extract at 1 h after or 1 before or together LPS (31.2 mg/kg) and the mediator production was evaluated at 0, 2, 4, 6, 12, and 24 hours as described in Methods. Each bar represents the standard deviation of 3 different experiments.