YAP Levels Combined with Plasma CEA Levels Are Prognostic Biomarkers for Early-Clinical-Stage Patients of Colorectal Cancer

Table 1

Relationship between YAP expressions and clinicopathologic features in colorectal cancers.

Features	Total	High YAP	Low YAP		χ^2
All case	116	76	40
Age
<56 years	55	37	18	0.706	0.143
≥56 years	61	39	22
Gender
Male	56	32	24	0.067	3.361
Female	60	44	16
Tumor size
<3 cm	45	31	14	0.543	0.370
≥3 cm	71	45	26
Differentiation
Low	15	10	5	0.712	0.137
Moderate	36	26	10
High	65	40	25
Serosal invasion
N	46	25	21	0.040	4.209
Y	70	51	19
Lymphatic metastasis
N	43	22	21	0.013	6.232
Y	73	54	19
LNR
<28	54	30	24	0.035	4.438
≥28	62	46	16
Remote metastasis
N	90	54	36	0.020	5.410
Y	26	22	4
Dukes stage
A and B	51	28	23	0.033	4.540
C and D	65	48	17
CEA
≤5 ng/ml	40	20	20	0.011	6.507
>5 ng/ml	76	56	20

Note. Statistically significant (). Abbreviations: LNR, lymph node ratio. LNR = positive lymph node/total examined lymph node × 100%. Tumor size was measured by the length of the largest tumor nodule.