Baicalin Protects against Thrombin-Induced Cell Injury in Human Umbilical Vein Endothelial Cells

Figure 3

Baicalin suppressed thrombin-induced the PAR-1 expression. Cells were treated as indicated, then total RNA was extracted for real-time RT-PCR analysis, and cells were lysed for western blotting analysis. (a) The quantitation represents the average relative ratio of PAR-1 mRNA to β-actin. (b) Representative experiments of western blot for the PAR-1 protein expression. (c) The quantitation represents the average relative ratio of PAR-1 protein to GAPDH. Values are means ± SD (n=3). ## P<0.01 vs. control group; P<0.05, P<0.01, and P<0.001 vs. thrombin group.

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