Research Article

Alda-1 Prevents Pulmonary Epithelial Barrier Dysfunction following Severe Hemorrhagic Shock through Clearance of Reactive Aldehydes

Table 1

Baseline characteristics of experimental animals.

MeasurementShamHemorrhagic shock + Placebo groupHemorrhagic shock + Alda-1 group

Body weight (g)362.50 ± 6.45365.00 ± 9.26365.00 ± 10.00
Heart rate (beats·min-1)383.00 ± 16.46406.50 ± 28.46395.75 ± 12.88
MAP (mmHg)122.75 ± 5.68120.12 ± 6.87122.12 ± 6.49
Lactate (mmol/L)0.90 ± 0.180.84 ± 0.380.80 ± 0.31
PH7.44 ± 0.027.41 ± 0.027.41 ± 0.05

MAP, mean aortic pressure. Values are presented as mean ± SD.