Research Article
Protective Effect of Genistein on Condylar Cartilage through Downregulating NF-κB Expression in Experimentally Created Osteoarthritis Rats
Figure 2
Treatment effects of GE on condyle cartilage changes in the rat model of TMJOA. (a) Representative histology changes in the condyle cartilage for the OA and GE treatment animals at 4 weeks after injection by HE staining. (b) Demonstration of matrix changes by Masson staining. (c) Quantitation of histology changes by the modified Mankin score system. The histological evaluation included 4 aspects. HE staining for the evaluation of structural integrity, cellularity, and tidemark integrity and Masson-stained sections for the evaluation of the cartilage matrix. Quantitative data are shown as means ± SD. , , significantly different when compared with NC and OA groups, respectively, n = 6.
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