Protective Effect of Genistein on Condylar Cartilage through Downregulating NF-κB Expression in Experimentally Created Osteoarthritis Rats

Figure 4

Effects of GE on the gene expression of IL-1β and TNF-α. (a) IL-1β expression in OA animals increased significantly compared with the NC group, while high dose of GE could significantly inhibit IL-1β expression. (b) TNF-α expression increased significantly in OA animals, and high dose of GE treatment could significantly inhibit TNF-α expression. Quantitative data are shown as means ± SD. , , , significantly different when compared with NC and OA groups, respectively, n = 6.

(a)

(b)