Pentraxin 3 Detects Clinically Significant Fibrosis in Patients with Chronic Viral Hepatitis C

Figure 1

PTX3 in histological scores of inflammatory activity and fibrosis in patients with chronic hepatitis C. (a) PTX-3 and METAVIR inflammation score (0-3); < 0.01 between scores of inflammatory activities A0-A1 and A2; < 0.001 between scores of inflammatory activities A0-A1 and A3 and A2 and A3; (b) PTX3 and METAVIR fibrosis score (0-4); < 0.01 between fibrosis stages F0-F1 and F≥2; (c) < 0.001 between fibrosis stages F0-F2 and F≥3. The top and bottom of each box represent the first and third quartiles, respectively, with the height of the box representing the interquartile range, covering 50% of the values. The line across each box represents the median. The whiskers show the highest and lowest values.

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