Pentraxin 3 Detects Clinically Significant Fibrosis in Patients with Chronic Viral Hepatitis C
Table 2
Univariate ordered logistic regression analysis with METAVIR fibrosis score as the dependent variable in patients with chronic HCV.
Variable
Coefficient (95% CI)
Standard error
Wald
P value
[PTX3 (ng/mL)]
1.945 (1.772-2.123)
0.238
66.78
< 0.01
[TGF-β1 (pg/mL)]
2.803 (2.517-3.008)
0.286
96.06
< 0.01
[Platelets (x 109/L)]
0.982 (0.967- 1.008)
0.180
29.76
< 0.01
[GGT (IU/L)]
1.245 (1.117-1.366)
0.248
25.20
< 0.01
[HA (ng/mL)]
1.312 (1.136-1.488)
0.321
16.70
< 0.01
[ALT (IU/L)]
1.016 (1.004-1.034)
0.360
8.667
< 0.05
[AST (IU/L)]
1.034 (1.014-1.116)
0.412
6.300
< 0.05
[INR]
1.033 (1.025-1.048)
0.363
8.101
< 0.05
[Bilirubin (mg/dL)]
1.042 (1.029-1.062)
0.382
7.442
> 0.1
[Albumin (g/dL)]
1.062 (1.033-1.117)
0.681
2.430
> 0.1
[Age (years)]
1.099 (0.885-1.455)
0.331
11.022
< 0.01
Data were analyzed by use of ordered logistic regression analysis. CI, confidence interval; HA, hyaluronic acid; INR, normalized international ratio; OR, odds ratio; TGF-β1, transforming growth factor‐β1.
