BioMed Research International / 2019 / Article / Tab 1 / Research Article
Development of an Empirically Calibrated Model of Esophageal Squamous Cell Carcinoma in High-Risk Regions Parameter Expected value (SD) Source Progression Normal → BCH/mD β 0 = -8.96 (0.461)Derived from calibration β 1 = 0.20481 (0.01815)β 2 = 0.00002 (0)β 3 = 0.00836 (0.00134) BCH/mD → MD α 0 = -3.359 (0.171)Derived from calibration α 1 = 0.03668 (0.0095) MD → SD 15.38% Derived from calibration SD → Undetected ESCC (TNM I) 20.94% [9 ] Undetected ESCC (TNM I) → Undetected ESCC (TNM II) 15.38% Derived from calibration Undetected ESCC (TNM II) → Undetected ESCC (TNM III) 20.94% Derived from calibration Undetected ESCC (TNM III) → Undetected ESCC (TNM IV) 46.65% Derived from calibration Detection rate Undetected ESCC (TNM I) → Detected ESCC (TNM I) 54.87% Derived from calibration Undetected ESCC (TNM II) → Detected ESCC (TNM II) 32.31% Derived from calibration Undetected ESCC (TNM III) → Detected ESCC (TNM III) 3.86% Derived from calibration Undetected ESCC (TNM IV) → Detected ESCC (TNM IV) 34.32% Derived from calibration Mortality All-cause mortality Chinese life-table [10 ] Disease-specific mortality (TNM I) Chinese life-table [10 ] Disease-specific mortality (TNM II) 15.15% [11 , 12 ] Disease-specific mortality (TNM III) 35.97% [11 , 12 ] Disease-specific mortality (TNM IV) 56.47% [11 , 12 ]
It was assumed to be equivalent with normal population after complete resection.
ESCC, esophageal squamous cell carcinoma; BCH, basal cell hyperplasia; mD, mild dysplasia; MD, moderate dysplasia; SD, severe dysplasia.
