Research Article

Comparative Genomic Analysis of Trichinella spiralis Reveals Potential Mechanisms of Adaptive Evolution

Table 2

T. spiralis PSGs encoding differentially expressed proteins in adults, muscle larvae and newborn larvae stages.

Accession No.DescriptionRatioRatioRatio
ML/Ad3ML/NBLAd3/NBL

E5S768/EFV59360.1putative chitin binding peritrophin-A domain protein2.260.542.89

E5SCG4/EFV57539.1angiotensin-converting enzyme, testis-specific isoform1.852.750.36

E5SG15/EFV56231.1putative IQ calmodulin-binding motif protein0.622.120.55

E5SJW0/EFV54917.1dimethylaniline monooxygenase [N-oxide-forming] 4---2.01---

E5SCL8/EFV57458.1gamma-glutamyltranspeptidase 1---2.58---

E5SHM8/EFV55721.1diacylglycerol O-acyltransferase 21.74------

E5SEH3/EFV56859.1G2/mitotic-specific cyclin-B3------2.26

E5S186/EFV61456.1leucine-rich repeat and fibronectin type-III domain-containing protein 4---3.06---

E5S732/EFV59418.1Putative fibronectin type III domain protein---2.60---

E5SK45/EFV54875.1putative cadherin domain protein, partial---3.06---

E5S9G6/EFV58492cystathionine beta-synthase2.140.56---

E5S621/EFV59764.1mitochondrial pyruvate carrier (brain protein 44)------1.75

E5S718/EFV59404.1putative proton-coupled amino acid transporter 42.11------

E5RYX1/EFV62291.1Y+L amino acid transporter 1---2.51---

E5SFC3/EFV56520.1excitatory amino acid transporter 1---2.25---

E5S9E0/EFV58588.1lonCoA ligase 51.600.52---

E5SGN7/EFV56123.1fatty acid synthase1.69---1.76

E5S673/EFV59699.1GDP-L-fucose synthetase2.20---1.88

E5RYD9/EFV62441.1phosphoglucomutase-22.29------

E5SGM8/EFV56114.1phosphomevalonate kinase1.62---1.94

E5SJ10/EFV55223.1calcium/calmodulin-dependent 3′,5′-cyclic nucleotide phosphodiesterase1C---3.93---

E5S2V7/EFV60868.1conserved hypothetical protein1.90---1.93

E5SEI1/EFV56867.1conserved hypothetical protein---2.41---

E5S2J6/EFV60967.1hypothetical protein Tsp_030592.812.22---

E5S923 /EFV58705.1small G protein signaling modulator 3-like protein1.63------

E5SFG5/EFV56461.1activating signal cointegrator 1---2.08---

E5SBW7/EFV57723.1extracellular signal-regulated kinase 1------1.91

E5SIP9/EFV55337.1transcriptional adapter 2-beta1.64---1.98

E5SIM1/ EFV55358.1putative BTB/POZ domain protein2.08------

E5S9P2 /EFV58568.1putative PDZ domain protein1.77------

E5SEX3/EFV56656.1diphthamide biosynthesis protein 11.77---2.10

E5S3A2/EFV60724.1zinc finger protein---0.552.02

E5S8F0/EFV58915.1putative actin-binding protein anillin---0.292.71

E5SFF4/EFV56450.1GTP-binding ADP-ribosylation factor---2.44---

E5SFH3/EFV56469chromatin regulator subfamily B member 11.60------

E5SB63/EFV58014.1DNA topoisomerase 2-alpha------1.78

E5SGN0/EFV56116.1histone acetyltransferase type B catalytic subunit------1.93

E5S4U4/EFV60187.1putative thromboxane-A synthase---2.58---

E5SJ08/EFV55221.1eukaryotic translation initiation factor 3 subunit E, partial---3.39---

E5RZQ0/EFV61978.1hint module superfamily---6.66---

E5SWW7/EFV50703.1putative irregular chiasm C-roughest protein---2.01---

E5S3J0/EFV60653.1conserved hypothetical protein1.960.40---

E5S3I6/EFV60649.1conserved hypothetical protein---2.54---

E5SIR3/EFV55280.1conserved hypothetical protein---2.02---

E5S3U6/EFV60533.1cuticle collagen 34 protein0.280.450.59

E5SC11/EFV57673.1Gut-specific cysteine proteinase---0.56---

E5S2Q2/EFV60927.1pyruvate dehydrogenase complex, E1 component,
pyruvate dehydrogenase, beta subunit0.63---0.58

E5SET0/EFV56681.1bestrophin-10.55---0.46

E5SC18/EFV57649.1protein phosphatase PTC7-like protein------0.61

E5S7E3/EFV59293.1phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN---0.45---

E5S8M1/EFV58830.1Phosphoribosyl pyrophosphate synthetase-associated protein 20.60------

E5SK74/EFV54817.1putative BAR domain protein0.65---0.60

E5RZN4/EFV61962.1putative peptidase dimerization domain protein---0.55---

E5SU43/EFV51698.1conserved hypothetical protein0.45---0.40

E5S2M0/EFV60948.1conserved hypothetical protein, partial0.57---0.53

E5RYF1/EFV62453.1conserved domain protein---0.46---

E5SDL6/EFV57109.1conserved hypothetical protein0.24---0.19

Differentially expressed proteins were defined using isobaric tags for relative and absolute quantitation (iTRAQ) as those with at least a 1.5 fold change relative to one another, with p < 0.05. Ratio data shows stage specific expression of proteins from Liu et al, 2016 [21]. ML, mature larvae, Ad3, adult L3 larvae, NBL, newborn larvae.