Research Article

Heart Failure Duration Combined with Left Atrial Dimension Predicts Super-Response and Long-Term Prognosis in Patients with Cardiac Resynchronization Therapy Implantation

Table 1

Baseline characteristics of patients between super-responders and non-super-responders.

characteristicsTotal populationsuper-respondersnon-super-respondersP Value
(n=73)(n=17)(n=56)

Age (years)60.32 ± 9.7860.00 ± 9.8761.35 ± 9.720.621
Gender (female)21 (28.8%)7 (41.2%)14 (25.0%)0.197
NYHA class3 (3-3)3 (2-3)3 (3-3)0.285
HF duration (months)48 (18-78)12 (6-60)60 (27-96)< 0.001
Hypertension, n (%)16 (21.9%)5 (29.4%)11 (19.6%)0.394
Diabetes, n (%)8 (11.0%)3 (17.6%)5 (8.9%)0.378
Atrial fibrillation, n (%)9 (12.3%)1 (5.9%)8 (14.3%)0.675
Ischemic etiology, n (%)12 (16.4%)4 (23.5%)8 (14.3%)0.456
LVEF (%)32 (27-34)32.6 (28-35)31 (25-33.75)0.140
LAD (mm)45 (39.75-47)40 (38-42)46 (41.23-48)0.001
LVEDD (mm)70.22 ± 7.9868.25 ± 8.3770.82 ± 7.840.247
MR (cm2)7.0 (4.5-9.98)5.99 (4.30-7.55)7.32 (4.5-10.41)0.079
QRS duration (ms)164.0 ± 20.99171.2 ± 16.54161.9 ± 21.830.109
LBBB, n (%)46 (63.0%)15 (88.2%)31 (55.4%)0.020
ACE-I/ARB, n (%)67 (91.8%)16 (94.1%)51 (91.1%)1.000
Beta-blockers, n (%)66 (90.4%)16 (94.1%)50 (89.3%)1.000
Spironolactone, n (%)61 (83.6%)15 (88.2%)46 (82.1%)0.720

Values are mean ± SD, median (range), or n (%).
NYHA: New York Heart Association; HF: Heart Failure; LVEF: left ventricular ejection fraction; LAD: left atrial dimension; LVEDD: left ventricular end-diastolic dimension; MR: mitral regurgitation; LBBB: left bundle branch block; ACEI: angiotensin-converting-enzyme inhibitor; ARB: angiotensin receptor blocker.