Research Article

Gadolinium Retention and Clearance in the Diabetic Brain after Administrations of Gadodiamide, Gadopentetate Dimeglumine, and Gadoterate Meglumine in a Rat Model

Figure 1

Study schemes. Both diabetic rats and healthy rats received 20 daily administrations of GBCAs and were allocated to 2 subgroups based on the time-point for subsequent analysis. For the 7-day subgroup, 6 rats underwent ICP-MS. For the 42-day subgroup, 6 rats underwent T1-weighted MRI (once a week) and ICP-MS, and 1 rat was analyzed by TEM.