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| GO ID | GO name | DEG number | value | FDR | Gene symbols |
|
| GO:0044281 | Small molecule metabolic process | 121 | 1.65E − 34 | 4.62E − 31 | PPP1CB|PLCB1|CALM1|PIK3CD|PIK3R1|PIK3CA|PTEN|LYPLA1|AMD1|SACM1L|ARF3| INSIG1|PDK3|ABHD5|CHKB|IMPA1,… |
| GO:0007165 | Signal transduction | 100 | 1.19E − 31 | 1.66E − 28 | IL7R|TNFSF12|TNFSF10|TNFSF4|PPP2R5C|PLCB1|CALM1|PIK3CB|PIK3CD|CASP1| TLR1| RAC2|STAT6|MAPK14|CAMK1|PAK2,… |
| GO:0045087 | Innate immune response | 64 | 1.57E − 24 | 1.47E − 21 | CASP1|ATF1|PIK3CA|PIK3R1|MAP3K7|MAP3K5|KRAS|TLR1|PTEN| |
| ATF2|CFP|PTPN11| IRF7|ACTB|CALM1,… | | | | | |
| GO:0010467 | Gene expression | 69 | 1.53E − 23 | 1.07E − 20 | TNFSF13|PPP2R1A|RPL38|MAPK14|KARS|SMAD2|AIMP1|DICER1,… |
| GO:0006915 | Apoptotic process | 66 | 5.32E − 22 | 2.98E − 19 | IL1A|TNFSF10|TNFSF12|MAP3K7|CASP1|BAX|RAD21|DICER1|CASP4|PTEN|H1F0|FXR1|PSMD12|DAB2|CST3,… |
| GO:0000278 | Mitotic cell cycle | 47 | 2.64E − 20 | 1.23E − 17 | PPP1R12A|PPP1CB|PPP2R1A|NSL1|RFC5|RAD21|RBL2|RPA1|CEP63… |
| GO:0006351 | Transcription, DNA-dependent | 114 | 1.32E − 19 | 5.28E − 17 | MAP3K7|ATF1|ATF6|STAT6|FOSL2|ASF1A|BBX|UCHL5|ATXN1|INO80 B|KANK2|CEBPE|SIRT1| SETD2|IRF5| BRD2|IKZF1|RB1,… |
| GO:0019221 | Cytokine-mediated signaling pathway | 27 | 1.63E − 19 | 5.70E − 17 | IL1A|IL6R|STAT2|STAT6|KRAS|CEBPA|PTPN11|CD44|IRF7|IRF5|IRF3|IRAK3|ZC3H15|CCR1,… |
| GO:0019048 | Virus-host interaction | 42 | 4.74E − 19 | 1.48E − 16 | MAP3K5|PIK3R1|KARS|BAX|TGFB1|CCR3|MDFIC| RB1|SIRT1,… |
| GO:0006468 | Protein phosphorylation | 43 | 2.25E − 18 | 6.30E − 16 | MAP3K11|MAP4K4|PIK3R1|PIK3CA|TGFB1|ADAM10|IRAK3|HIPK3|SMAD2| TLK1|CREB1|FYB|STK11,… |
| GO:0008380 | RNA splicing | 34 | 3.49E − 16 | 7.52E − 14 | PPP2R1A|SRSF11|PABPN1|CPSF1|SRSF3|CLASRP,… |
| GO:0015031 | Protein transport | 43 | 3.87E − 16 | 7.73E − 14 | RAB3D|ARRB2|RAB11A|ACAP1|NMD3|ARF3,… |
| GO:0044267 | Cellular protein metabolic process | 45 | 4.71E − 13 | 6.94E − 11 | ATF1|RPL38|ACTB|ATF6|CPA3|EIF4B|ETF1|SPCS2|CXXC1|ALG5|CCT6A,… |
| GO:0000090 | Mitotic anaphase | 24 | 4.61E − 12 | 5.87E − 10 | PPP2R1A|RAD21|PDS5A|PSMD3|SMC3|CLASP2,… |
| GO:0000087 | M phase of mitotic cell cycle | 26 | 7.27E − 12 | 8.85E − 10 | PPP2R1A|PSMD4|CLASP2|PSME3|ANAPC5|RAD21|RANBP2,… |
| GO:0000398 | mRNA splicing via spliceosome | 24 | 7.84E − 12 | 9.15E − 10 | SRSF11|PABPN1|CLP1|RBM22|PAPOLA|FUS|POLR2E|TRA2A|PRPF4B,… |
| GO:0001525 | Angiogenesis | 24 | 9.13E − 12 | 1.02E − 09 | TNFSF12|MAP3K7|MAPK14|PIK3CA|ELK3|DICER1|SIRT1,… |
| GO:0002224 | Toll-like receptor signaling pathway | 19 | 3.87E − 11 | 3.87E − 09 | MAP3K7|MAPK14|TLR7|IRF7|ATF1|ATF2|DUSP3|IRF3|HSP90B1|RPS6KA5|BTK| UNC93B1|ELK1|BCL10|UBE2D1,… |
| GO:0007049 | Cell cycle | 24 | 4.71E − 11 | 4.55E − 09 | PPP1CA|CAMK1|RB1CC1|CREBL2|PARD6A|CYLD|TLK1| IKZF1,… |
| GO:0006955 | Immune response | 29 | 7.21E − 11 | 6.73E − 09 | IL1A|IL7R|IL1RN|TNFSF10|TNFSF4|TNFSF13|TLR1|CCR1|IKBKAP,… |
| GO:0008283 | Cell proliferation | 29 | 5.42E − 10 | 4.27E − 08 | IL1A|RBL38|MAP3K11|PTEN|DAB2|FES|PA2G4|ASCC3|MS4A2,… |
| GO:0030155 | Regulation of cell adhesion | 10 | 5.49E − 10 | 4.27E − 08 | PPP2R1A|PPP1R12 A|PPP1CB|CYTH4|PTK2B| CYTIP| ENG|GSN,… |
| GO:0050852 | T-cell receptor signaling pathway | 16 | 6.55E − 10 | 4.96E − 08 | MAP3K7|PIK3CA|PIK3CB|PIK3R1|PIK3CD|RBCK1|PAK2|FYB|UBE2N|PTEN|WAS|FYN|NCK1|MALT1|CD4| BCL1 |
| GO:0043065 | Positive regulation of apoptotic process | 20 | 8.03E − 10 | 5.92E − 08 | TNFSF10|PPP2R4|MAP3K5|PIK3R1|TGFB1|ATM|SIRT1|DNM2|LILRB1|CTNNB1|TSPO|HMGB1|BAX|ING3|IRF5|PRKDC,… |
| GO:0051403 | Stress-activated MAPK cascade | 10 | 1.92E − 09 | 1.38E − 07 | MAPK14|MAP3K7|ATF1|ATF2|ELK1|DUSP3|RPS6KA3|CREB1|RPS6KA1|RPS6KA5 |
| GO:0007010 | Cytoskeleton organization | 10 | 4.27E − 09 | 2.49E − 07 | PRPF40 A|PHIP|SIPA1|PLD2|SVIL|PXN|TPM1|ZMYM4|CAPZB,… |
| GO:0050900 | Leukocyte migration | 14 | 6.19E − 09 | 3.54E − 07 | PIK3CB| PIK3CA|PIK3R1|KRAS|SIRPA| PTPN11|FYN|ITGB7,… |
| GO:0006954 | Inflammatory response | 19 | 1.11E − 08 | 6.21E − 07 | IL1A|PIK3CD|TLR1|TLR7|STAB1|TGFB1|HRH4|CCR3|CCR1|LTB4R,… |
| GO:0008219 | Cell death | 16 | 8.44E − 08 | 3.94E − 06 | MAP3K11|BCL10|FOSL2|CLN3|ATXN7|DCTN1|FUS|,… |
| GO:0006281 | DNA repair | 30 | 9.06E − 08 | 4.16E − 06 | BTG2|RFC5|SMC3|RPA1|TDG|CSNK1D|REV1,… |
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