|
| Pathway name | DEG number | value | Gene symbols |
|
| Osteoclast differentiation | 26 | 6.26E − 16 | TYK2|PIK3CA|PIK3CB|PIK3CD|PIK3R1|IL1A|PPP3CA|JUND|FOSL2|MAPK14|MAP3K7|STAT2|TGFB1,… |
| Metabolic pathways | 79 | 2.81E − 15 | COX11|PIP5K1A|PLCB1|CHPF2|ALOX5|TPK1,… |
| PI3K-Akt signaling pathway | 34 | 1.77E − 11 | IL7R|IL6R|PPP2R5C|PPP2R1A|PIK3CB|PIK3CD|PIK3CA|ATF2,… |
| MAPK signaling pathway | 28 | 1.34E − 10 | IL1A|PPP3CA|JUND|MAPK14|MAP3K5|MAP3K7|KRAS|TGFB1,… |
| Chemokine signaling pathway | 24 | 1.39E − 10 | PLCB1|CCR1|CCR3|PIK3R1|PIK3CD|PIK3CB|PIK3CA|KRAS|RAC2|STAT2,… |
| T-cell receptor signaling pathway | 17 | 2.29E − 09 | PPP3CA|MAPK14|MAP3K7|PIK3CD|PIK3CB|PIK3R1|PIK3CA|KRAS|BCL10,… |
| Focal adhesion | 23 | 3.28E − 09 | PPP1CA|PPP1CB|ACTB|PIK3CA|PIK3CD|PIK3CB|PTEN,… |
| Apoptosis | 15 | 6.96E − 09 | IL1A|TNFSF10|TNFRSF10B|PIK3CD|PIK3CB|PIK3CA|BAX|IRAK3,… |
| Pathways in cancer | 27 | 9.27E − 08 | PIK3CA|PIK3CB|PIK3R1|PIK3CD|KRAS|PTEN|MAX|RAC2,… |
| Cell cycle | 16 | 1.29E − 07 | ANAPC5|TGFB1|SMAD2|ATM|RBL2|RB1,… |
| VEGF signaling pathway | 11 | 1.26E − 06 | PPP3CA|MAPK14|PIK3CA|PIK3CD|PIK3R1|PIK3CB|RAC2|KRAS,… |
| Toll-like receptor signaling pathway | 11 | 1.37E − 04 | MAPK14|MAP3K7|PIK3CD|PIK3R1|PIK3CA|PIK3CB|TLR7|TLR1|IRF5|IRF7,… |
| Calcium signaling pathway | 14 | 3.47E − 04 | PPP3CA|PLCB1|CALM1|ITPR1|ITPR2|PTK2B,… |
| p53 signaling pathway | 8 | 4.91E − 04 | TNFRSF10B|ATM|PTEN|THBS1|BAX|CCNG2|CCNG1,… |
| Wnt signaling pathway | 10 | 5.49E − 03 | PPP3CA|MAP3K7|PLCB1|RAC2|CHP|,… |
| TGF-β signaling pathway | 7 | 7.29E − 03 | PPP2R1A|TGFB1|SMAD2|SMURF2,… |
| Jak-STAT signaling pathway | 10 | 1.11E − 02 | IL7R|IL6R|PIK3R1|PIK3CA|PIK3CD|PIK3CB|STAT2|STAT6,… |
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