Prediction of MicroRNA and Gene Target in Synovium-Associated Pain of Knee Osteoarthritis Based on Canonical Correlation Analysis

Figure 4

Classification performance analysis of four genes overlapped with synovial pain knee OA genes identified in the OMIM database. (a) ROC analysis of the four genes: TGFBR2, DST, TBXAS1, and FHL1. AUC was above 0.8. Classification accuracy was above 80%. (b) Classification accuracy of the four genes based on the SVM method. (c, d) The SVM classification diagram of TGFBR2, DST, TBXAS1, and FHL1. OMIM: Online Mendelian Inheritance in Man; ROC: receiver operating characteristic curve; AUC: area under the Curve; SVM: support vector machine.

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