Fecal Microbiota of Diarrhea-Predominant Irritable Bowel Syndrome Patients Causes Hepatic Inflammation of Germ-Free Rats and Berberine Reverses It Partially

Figure 1

Hepatic inflammation caused by IBS-D. (a) HE and immunohistochemical staining of the liver, hepatic sinusoid expansion score, and number of KCs with hyperplasia. (b) TNF-α and IFN-γ were examined by western blotting, and each expression was quantified by Gel-pro software. (c) Statistical analysis of serum biochemical parameters. p<0.05; p<0.01; p<0.001.

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