Molecular Modelling and Dynamics Study of nsSNP in STXBP1 Gene in Early Infantile Epileptic Encephalopathy Disease

Figure 5

Backbone Root Mean Square Fluctuation (RMSF) of the wild type STXBP1 protein and its mutant forms for 5000ps of molecular dynamics simulation. Color scheme: (a) a wt-STXBP1 (black) and H103D (cyan), (b) wt-STXBP1 (black), S42P (red) and L256P (yellow), (c) wt-STXBP1 (black), C354Y (green) and L365V (magenta), (d) wt-STXBP1 (black), R190W (blue), R235G (brown) and D238E (orange), (e) wt-STXBP1 (black) and R406C (grey), (f) wt-STXBP1 (black), P335S (violet) and G544D (maroon).

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