Decision Support Systems in Prostate Cancer Treatment: An Overview

Table 4

Overview of excluded studies that described tools to improve mDSS.

Study	N	Tool	Inputs	Outcomes
(Daemen et al. 2009)[61]	55	Genetic integration	DNA, CNV	Cancer outcome
(Kuru et al. 2013)[59]	50	Diagnostics	mpMRI	PIRADS
(Zumsteg et al. 2013)[55]	1024	Risk stratification	Risk factors, Gleason score, biopsy	Risk group
(Beyan et al. 2014) [62]	Model	Genetic integration	SNPs	Various
(Kent and Vickers 2015)[60]	Model	Diagnostics	Clinical and tumor features	Life expectancy
(Gnanapragasam et al. 2016)[56]	10139	Risk stratification	PSA, stage, Gleason score	Risk group
(Epstein et al. 2016)[57]	26325	Risk stratification	PSA, stage	Gleason grade
(Gries et al. 2017)[58]	120	Utility values	Utility’s 18 health states	Utility’s 243 heath states

Abbreviations. N: Number of patients; CNV: copy number variation; SNP: single nucleotide polymorphism; PSA: prostate specific antigen; mpMRI: multiparametric magnetic resonance imaging; PIRADS: Prostate Imaging Reporting and Data system.