Tranexamic Acid Reduces Total Blood Loss and Inflammatory Response in Computer-Assisted Navigation Total Knee Arthroplasty

Table 2

Postoperative parameters.

	TXA, N = 103	Control, N = 119	value
POD1
Hb (g/dL)	11.48 ± 1.16	11.08 ± 1.31	0.011
Hct (%)	34.67 ± 3.33	33.00 ± 3.76	<0.001
D-dimer (mg/L)	5.70 ± 5.39	6.63 ± 6.38	0.307
Hb drop (g/dL)	1.34 ± 0.88	2.10 ± 0.99	<0.001
Fibrinogen (mg/dL)	296.48 ± 49.01	282.29 ± 51.68	0.013
POD3
Hb (g/dL)	10.32 ± 1.15	9.71 ± 1.29	<0.001
Hct (%)	31.15 ± 3.45	29.10 ± 3.81	<0.001
D-dimer (mg/L)	1.95 ± 0.99	3.16 ± 1.79	<0.001
Hb drop (g/dL)	2.51 ± 0.89	3.48 ± 1.13	<0.001
Fibrinogen (mg/dL)	549.82 ± 128.34	485.74 ± 111.84	<0.001
Platelet (1000/μL)	176.24 ± 38.40	181.08 ± 47.11	0.587
POD1 ETBL (ml)	404.34 ± 234.77	595.47 ± 279.04	<0.001
POD2 ETBL (ml)	761.39 ± 260.88	987.79 ± 326.58	<0.001
Transfusion rate (%)	0	2 (1.7%)	0.501

Hb: hemoglobin; Hct: hematocrit; ETBL: estimate total blood loss.