The Alcohol Extract of Coreopsis tinctoria Nutt Ameliorates Diabetes and Diabetic Nephropathy in db/db Mice through miR-192/miR-200b and PTEN/AKT and ZEB2/ECM Pathways

Table 3

Effect of AC on HbA1c and kidney/weight ratio in each group (±SE).

Group	HbA1c (%)	K/W
NC	4.12±0.11	5.88±0.15
DN	7.61±0.31	7.47±0.70
DN+M	7.20±0.42	5.14±0.41#
DN+AC	6.53±0.41	5.20±0.43#

Note: NC: normal control mice, DN: diabetic nephropathy mice, DN+M: DN mice given 180 mg/kg metformin, and DN+AC: DN mice given 300 mg/kg AC. K/W: Kidney/weight ratio. : P<0.05 compared with the NC group; #: P<0.05 compared with the DN group.