Caffeic Acid Phenethyl Ester (CAPE) Induces VEGF Expression and Production in Rat Odontoblastic Cells

Figure 3

Comprehensive expression analysis of osteogenesis-related genes in CAPE-treated KN-3 cells by PCR array. Total RNA was isolated from KN-3 cells stimulated with CAPE for 6 hours in normal medium and reverse-transcribed into cDNA. The expression profiles of genes involved in bone metabolism, growth factors, and differentiation were analyzed using PCR array. The level of VEGF mRNA expression increased 5.66-fold by CAPE treatment.