Phosphocreatine Attenuates Isoproterenol-Induced Cardiac Fibrosis and Cardiomyocyte Apoptosis

Figure 1

PCr inhibited ISO-induced cardiac fibrosis. (a-b) Picrosirius red staining and the CVF of each group. (c-d) Laminin level between each group. (e–h) Western blots and quantification of collagen I, collagen III, TGF-β1, and α-SMA protein expression in left ventricular tissues. P<0.05, P<0.01, and P<0.001, versus the ISO group, n=8 per group. Scale bar=50 μm.

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