Phosphocreatine Attenuates Isoproterenol-Induced Cardiac Fibrosis and Cardiomyocyte Apoptosis

Table 1

Effect of PCr on the echocardiographic parameters of ISO-induced rats.

	Control	ISO	PCr
Heart rate, beats/min	416.25±11.90	490.38±14.2	481.88±11.6
LVDd, mm	6.38±0.26	5.91±0.2	6.06±0.2
LVDs, mm	3.33±0.18	2.30±0.1	2.39±0.2
IVST, mm	1.34±0.07	2.30±0.1	2.20±0.1
PWT, mm	1.21±0.10	1.55±0.0	1.48±0.1
EF, %	79.63±1.30	73.13±2.3	74.50±3.4
FS, %	42.88±2.03	33.75±2.1	34.75±2.6

The data are given as the mean ± SD. LVDd, left ventricular end-diastolic dimension; LVDs, left ventricular end-systolic dimension; PWT, left ventricular posterior wall thickness; IVST, inter ventricular septum wall thickness; EF, left ventricular ejection fraction; FS, fractional shortening. The data represent the mean ± SD. P < 0.05 versus control group. ^#: P < 0.01 versus control group, n=8 per group.