Long Noncoding RNA ASB16-AS1 Promotes Proliferation, Migration, and Invasion in Glioma Cells

Figure 1

Bioinformatic analysis. The top 10% hub nodes are shown in red, while the remaining hub nodes are shown in blue. lncRNAs are represented as diamonds; genes with protein products are shown as rectangles; and other molecules are shown as circles. (a) A total of 178 lncRNAs within the differentially expressed genes met the condition of area under the curve >0.85. The ceRNA network for those 178 lncRNAs was constructed based on data exported from starBase. Not all lncRNA data could be identified in starBase, and only 72 lncRNAs were identified in the ceRNA network. (b) Degree sorted circle layout of graph (b), which contains two circular layouts. lncRNAs are introduced in the inner circular layout, while other RNAs are located in the outer circular layout. (c) Zoom in an area of (b) to show the details of ASB16-AS1 in network. (d) Nodes directly connected with ASB18-AS1 in the ceRNA network. (e) Localization of ASB16 and ASB16-AS1 on chromosome 17. The figure was constructed based on information from UCSC Genome Browser (genome.ucsc.edu).

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