HOTTIP Functions as a Key Candidate Biomarker in Head and Neck Squamous Cell Carcinoma by Integrated Bioinformatic Analysis

Figure 5

Target gene prediction of HOTTIP and functional assessment. (a) Target genes of HOTTIP predicted by Multi-Experiment Matrix; (b) target genes of HOTTIP predicted by starBase; (c) correlation plots of HOTTIP expression and top 10 target genes in TCGA HNSCC cohort; (d)-(f) scatter plots of the correlation analysis of HOTTIP expression with HOXA13, HOXA10, and HOXA11; (g) enriched GO terms by target genes of HOTTIP; (h) HOTTIP-miRNA-mRNA network.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)