Hypoxia-Inducible Factor 1A Upregulates HMGN5 by Increasing the Expression of GATA1 and Plays a Role in Osteosarcoma Metastasis

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Group</td><td class="align_center">Overexpression</td><td class="align_center">Knockdown</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Cherry-GFP</td><td class="align_center">—</td><td class="align_center">—</td></tr><tr><td class="align_left">HIF1A<sup>OE</sup>-GFP</td><td class="align_center">HIF1A</td><td class="align_center">—</td></tr><tr><td class="align_left">HIF1A<sup>OE</sup>-HMGN5<sup>sh</sup></td><td class="align_center">HIF1A</td><td class="align_center">HMGN5</td></tr><tr><td class="align_left">HIF1A<sup>OE</sup>-GATA1<sup>sh</sup></td><td class="align_center">HIF1A</td><td class="align_center">GATA1</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

BioMed Research International

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Table 1

Table 1: Hypoxia-Inducible Factor 1A Upregulates HMGN5 by Increasing the Expression of GATA1 and Plays a Role in Osteosarcoma Metastasis 