Prognostic Nomogram for the Overall Survival of Patients with Newly Diagnosed Multiple Myeloma

Table 3

The C-indices for the nomogram and the five currently used staging systems for multiple myeloma to predict overall survival in patients.

Staging systems	Training cohort		Validation cohort
	C-index	95% CI	C-index	95% CI
Nomogram	0.749	0.693−0.805	0.711	0.650−0.772
ISS	0.576	0.515−0.637	0.637	0.553−0.720
R-ISS	0.625	0.567−0.683	0.651	0.566−0.736
D-S	0.567	0.510−0.624	0.529	0.446−0.612
mSMART	0.583	0.524−0.642	0.620	0.532−0.708
IMWG	0.513	0.453−0.573	0.578	0.484−0.672

Abbreviations: C-index, index of concordance; CI, confidence interval; ISS, International Staging System; R-ISS, Revised-International Staging System; D-S, Durie-Salmon Staging System; mSMART, Mayo Stratification of Myeloma and Risk-Adapted Therapy; IMWG, International Myeloma Working Group risk stratification.