Alleviation of Cartilage Destruction by Sinapic Acid in Experimental Osteoarthritis

Figure 3

Effects of SA on IL-1β-induced MMPs and ADAMTS5 expression. Cells were pretreated with SA (3, 9, 12 μg/ml) in the absence or presence of IL-1β (10 ng/ml) for 24 h. (a) Protein levels of MMPs and ADAMTSs were determined by western blot analysis. (b) Quantitative analysis of MMPs and ADAMTSs levels from (a). The bands are representative of three separate experiments. p < 0.05 compared with IL-1β treatment only.

(a)

(b)