GYY4137 Attenuates Sodium Deoxycholate-Induced Intestinal Barrier Injury Both In Vitro and In Vivo

Figure 4

The effects of GYY4137 on the status of P-MLCK-P-MLC2 signaling pathway in Caco-2 monolayers with short-term SDC treatment. Caco-2 monolayers were treated as described in Figure 3. (a–c) GYY4137 inhibited SDC-induced increased phosphorylation of MLCK and MLC2. Results were expressed as mean ± SEM (n = 3). vs. control. vs. SDC.

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