Research Article
Correlation between Serological Biomarkers and Disease Activity in Patients with Inflammatory Bowel Disease
Table 2
Demography and basic laboratory values of ulcerative colitis patients.
| | Variables | UC without CDI, inactive | UC without CDI, active | value | UC with CDI | value |
| | Total number (%) | 18 (24.7) | 37 (50.7) | | 18 (24.7) | | | Epidemiology | | Age (years), median (range) | 43.0 (25–58) | 43.0 (18–73) | 0.580 | 41.0 (24–69) | 0.823 | | Male gender (%) | 8 (44.4) | 21 (56.8) | 0.391 | 13 (72.2) | 0.091 | | BMI (kg/m2) (SD) | 21.1 (3.0) | 20.1 (2.3) | 0.171 | 21.7 (3.6) | 0.625 | | Laboratory examination | | WBC (109/L) (SD) | 8.6 (3.9) | 8.7 (4.2) | 0.923 | 11.6 (11.6) | 0.294 | | Neutrophil (109/L) (SD) | 6.0 (3.5) | 6.2 (4.0) | 0.819 | 6.3 (1.8) | 0.788 | | Lymphocyte (109/L) (SD) | 1.8 (0.7) | 1.4 (0.6) | 0.040 | 1.6 (0.6) | 0.404 | | Monocyte (109/L) (SD) | 0.6 (0.3) | 0.9 (0.5) | 0.023 | 0.9 (0.6) | 0.157 | | NLR | 3.8 (3.09) | 5.5 (6.2) | 0.273 | 4.2 (1.3) | 0.622 | | LMR | 3.5 (1.7) | 2.2 (1.6) | 0.011 | 2.5 (1.3) | 0.057 | | NMR | 10.0 (4.4) | 8.3 (5.3) | 0.255 | 9.8 (4.8) | 0.868 | | Hemoglobin (g/L) (SD) | 12.1 (2.0) | 11.5 (2.5) | 0.416 | 12.5 (2.9) | 0.679 | | CRP (mg/dl) (SD) | 12.2 (29.0) | 34.2 (40.3) | 0.043 | 37.1 (39.0) | 0.037 | | ESR (mm/h) (SD) | 18.2 (30.4) | 23.3 (21.0) | 0.465 | 18.8 (17.5) | 0.942 | | Albumin (g/L) (SD) | 37.3 (5.2) | 33.6 (7.1) | 0.054 | 35.7 (6.0) | 0.401 | | Fibrinogen (g/L) (SD) | 3.2 (1.1) | 3.8 (1.7) | 0.170 | 4.0 (1.0) | 0.035 |
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UC, ulcerative colitis; CDI, Clostridium difficile infection; SD, standard deviation; BMI, body mass index; WBC, white blood cells; NLR, neutrophil-to-lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio; NMR, neutrophil-to-monocyte ratio; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.
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