Research Article
Correlation between Serological Biomarkers and Disease Activity in Patients with Inflammatory Bowel Disease
Table 3
Demographic and basic laboratory values of Crohn’s disease patients.
| | Variables | CD without CDI, inactive | CD without CDI, active | value | CD with CDI | value |
| | Total number, n (%) | 85 (60.3) | 44 (31.2) | | 12 (8.5) | | | Epidemiology | | Age (years), median (range) | 32.0 (15–62) | 29.0 (15–59) | 0.86 | 30.0 (21–54) | 0.926 | | Male gender | 57 (67.1) | 25 (56.8) | 0.252 | 7 (58.3) | 0.550 | | BMI (kg/m2) (SD) | 18.7 (2.6) | 18.4 (2.7) | 0.546 | 18.7 (1.9) | 0.995 | | Laboratory examination | | WBC (109/L) (SD) | 6.5 (2.1) | 8.7 (3.2) | ≤0.001 | 6.9 (2.5) | 0.521 | | Neutrophil (109/L) (SD) | 4.5 (1.7) | 6.3 (2.8) | ≤0.001 | 4.8 (2.1) | 0.637 | | Lymphocyte (109/L) (SD) | 1.3 (0.5) | 1.3 (0.6) | 0.406 | 1.4 (0.7) | 0.454 | | Monocyte (109/L) (SD) | 0.5 (0.3) | 0.7 (0.3) | ≤0.001 | 0.5 (0.2) | 0.748 | | NLR | 4.0 (2.0) | 5.5 (4.5) | 0.010 | 4.1 (2.8) | 0.928 | | LMR | 3.1 (1.9) | 2.3 (1.2) | 0.009 | 3.2 (2.0) | 0.821 | | NMR | 10.6 (6.0) | 11.1 (9.2) | 0.709 | 10.7 (6.2) | 0.974 | | Hemoglobin (g/L) (SD) | 11.9 (1.9) | 11.1 (2.3) | 0.047 | 12.1 (1.2) | 0.751 | | CRP (mg/dl) (SD) | 19.3 (21.8) | 47.4 (47.2) | ≤0.001 | 35.6 (22.8) | 0.018 | | ESR (mm/h) (SD) | 21.4 (16.7) | 33.0 (25.1) | 0.002 | 20.3 (18.9) | 0.828 | | Albumin (g/L) (SD) | 33.6 (7.2) | 32.1 (6.7) | 0.262 | 35.2 (6.5) | 0.452 | | Fibrinogen (g/L) (SD) | 4.3 (1.2) | 4.8 (1.3) | 0.018 | 4.1 (1.0) | 0.605 |
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CD, Crohn’s disease; CDI, Clostridium difficile infection; SD, standard deviation; BMI, body mass index; WBC, white blood cells; NLR, neutrophil-to-lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio; NMR, neutrophil-to-monocyte ratio; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.
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