Diuretic and Antidiuretic Activities of Ethanol Extract and Fractions of Lagopsis supina in Normal Rats

Table 3

Effects of LS, LSA, LSB, LSC, and LSD on urinary electrolyte Na⁺ (mmol/L) concentrations within 1, 2, 4, 6, and 24 h after oral administration.

Group	1 h	2 h	4 h	6 h	24 h
Control	101.88 ± 7.77	100.38 ± 8.50	99.33 ± 9.33	100.18 ± 2.04	100.30 ± 3.87
Furosemide	59.75 ± 1.34	67.43 ± 8.02	84.65 ± 3.77	96.00 ± 5.53	111.80 ± 8.59
LS-H	111.80 ± 8.59	114.13 ± 8.26	117.45 ± 8.13	120.15 ± 7.29	119.80 ± 8.69
LS-M	101.55 ± 11.09	102.28 ± 9.82	107.48 ± 9.73	114.15 ± 11.83	120.68 ± 1.78
LS-L	118.20 ± 6.20	117.30 ± 7.47	116.58 ± 6.93	115.83 ± 6.51	108.20 ± 10.16
LSA-H	114.95 ± 18.99	116.13 ± 14.65	121.00 ± 17.08	125.00 ± 12.53	142.28 ± 18.97
LSA-L	75.98 ± 7.60	78.00 ± 4.45	91.18 ± 6.00	100.28 ± 6.75	121.70 ± 9.37
LSB-H	128.18 ± 2.54	124.05 ± 3.26	111.65 ± 5.31	107.83 ± 4.08	111.55 ± 4.57
LSB-L	115.78 ± 9.47	116.95 ± 17.14	109.33 ± 15.01	102.30 ± 11.55	91.00 ± 7.95
LSC-H	94.95 ± 4.84	94.90 ± 5.96	85.10 ± 7.54	83.05 ± 9.22	78.38 ± 8.23
LSC-L	114.73 ± 9.48	110.80 ± 7.39	111.38 ± 11.17	112.35 ± 6.18	126.13 ± 10.13
LSD-H	106.03 ± 7.42	98.60 ± 4.03	94.50 ± 3.89	88.10 ± 4.62	74.43 ± 7.09
LSD-L	115.55 ± 5.26	113.10 ± 4.52	107.33 ± 5.44	112.08 ± 2.39	118.63 ± 5.80

The values are reported as mean ± SD for 8 rats in each group. and compared to the control.