Research Article

Evaluation of Chondroprotective Activity of Channa striatus in Rabbit Osteoarthritis Model

Table 1

Histological assessment of articular cartilage in the ACLT rabbit model of OA Structure. Table 1 is reproduced from Laverty et al. (2010) and Gao et al (2013), ([under the Creative Commons Attribution License/public domain).
(a)

0normal
1Surface irregularities
2Fissures in < 50% surface
3Fissures in ≥ 50% surface
4Erosion 1/3 hyaline cartilage < 50% surface
5Erosion 1/3 hyaline cartilage ≥ 50% surface
6Erosion 2/3 hyaline cartilage < 50% surface
7Erosion 2/3 hyaline cartilage ≥ 50% surface
8Full depth erosion 2/3 hyaline cartilage < 50% surface
9Full depth erosion 2/3 hyaline cartilage ≥ 50% surface
10Full depth erosion hyaline cartilage and calcified cartilage to the subchondral bone < 50%
11Full depth erosion hyaline cartilage and calcified cartilage to the subchondral bone ≥ 50%

(b) Chondrocyte density

0No decrease in cells
1Focal decrease in cells
2Multifocal decrease in cells
3Multifocal confluent decrease in cells
4Diffuse decrease in cells

(c) Cluster formation

0normal
1 < 4 clusters
2≥ 4 but < 8 clusters
3 ≥ 8 clusters