Label-Free LC-MS/MS Proteomics Analyses Reveal Proteomic Changes Accompanying MSTN KO in C2C12 Cells

Figure 7

Differentially expressed proteins of KO relative to NC cells, as depicted in their networks by STRING and visualized by Cytoscape5 software. Each yellow dot represents a protein of interest found to be differentially expressed in the presence of MSTN KO by quantitative proteomics, and the lines represent putative protein interactions recorded or predicted by STRING. Green dots represent proteins of interest directly interacting with other proteins. (a) KO versus NC, analysis of significantly different proteins; (b) KO versus NC, analysis of present or absent proteins.

(a)

(b)