miRNA and mRNA Integration Network Construction Reveals Novel Key Regulators in Left-Sided and Right-Sided Colon Adenocarcinoma

Figure 4

Identification of optimal miRNA biomarkers between RSCOAD and LSCOAD. (a) Hierarchical clustering analysis of 22 DEmiRNAs. Row and column represent DEmiRNAs and tissue samples, respectively. Orange and light blue color mean the RSCOAD and LSCOAD, respectively. The color scale represents the expression levels. Red color represents that the relative expression level of genes was higher than mean, and green color represents that the relative expression of genes was lower than mean. (b) The ROC results of these 22 diagnostic miRNA biomarker based on random forest model.

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