Research Article

Does Pharmacological Treatment Reduce the Incidence of Lower Urinary Tract Symptoms (LUTS) after Transobturator Sling?

Table 4

The evolution of nocturia in the course of the study.

VariableBaseline
n (%) [B]
Week 1
n (%) [W1]
Week 6
n (%) [W6]
Statistical analyses inside each group

Control group
(n=110) 
C
16 (14.5)18 (16.4)8 (7.3)B vs.W1, NS
B vs. W6, NS
W1 vs. W6, p <0.05

Treatment group 1
(10 mg of solifenacin)
(n=114)  
S
19 (16.7)17 (14.9)5 (4.4)B vs.W1, NS
B vs. W6, p <0.005
W1 vs. W6, p <0.01

Treatment group 2
(50 mg of mirabegron)
(n=104)  
M
20 (19.2)17 (16.3)10 (9.6)B vs.W1, NS
B vs. W6, p <0.05
W1 vs. W6, NS

Baseline: C vs. S (NS); C vs. M (NS); S vs. M (NS).
Week 1: C vs. S (NS); C vs. M (NS); S vs. M (NS).
Week 6: C vs. S (NS); C vs. M (NS); S vs. M (NS).