Research Article

Levels of Selected Matrix Metalloproteinases, Their Inhibitors in Saliva, and Oral Status in Juvenile Idiopathic Arthritis Patients vs. Healthy Controls

Table 4

Correlations of MMPs and their inhibitors with clinical oral parameters in the course of JIA in the sample population.

Salivary parametersJIAC
DMFTDOHI-SGIPBISFDMFTDOHI-SGIPBISF

MMP-2r0.110.0050.360.280.26−0.370.080.2−0.120.140.12−0.10
p0.5380.970.0360.1090.1390.0330.6410.260.4850.4400.4880.576

MMP-8r0.160.140.210.260.26−0.220.110.19−0.040.190.190.18
p0.3530.4160.2420.1340.1430.2090.5220.290.8260.2750.2840.318

MMP-9r0.260.140.130.390.20−0.13−0.150.05−0.24−0.15−0.13−0.22
p0.1330.4210.480.0210.2570.4610.4040.780.1770.3980.4610.206

TIMP-1r0.15−0.02−0.010.380.30−0.300.080.24−0.17−0.01−0.05−0.26
p0.4050.90.940.0270.0800.0880.6690.170.3340.9400.7590.136

TIMP2r0.15−0.040.090.290.20−0.31−0.150.12−0.31−0.16−0.04−0.25
p0.4020.80.60.0920.2480.0760.4060.50.0790.3750.8230.155

Note. Spearman’s rank correlation; statistically significant.